Strategy and statistics in clinical trials : a non-statisticians guide to thinking, designing, and executing - Tal, Joseph (Amsterdam ; Boston : Academic Press, 2011)
Clinical development and statistics: the general view -- Questions for planning trials -- Medical product attributes -- Setting research objectives -- Statistical thinking -- Estimation -- From description to testing: a beginning -- Statistical significance, explanation and prediction -- Exploratory and confirmatory clinical trials -- One, two, three testing: hypothesis testing and multiplicity -- Elements of clinical trial design I: putting it together -- Elements of clinical trial design II -- Endpoints -- Sample size -- Concluding remarks
Includes bibliographical references and index
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Keywords: Clinical trials -- Statistical methods; Statistics as Topic